Curriculum vitæ

Diego Mariano

Nationality: Brazilian | Age: | Contact: diegocbmariano @

Ph.D. and M.S. in Bioinformatics by the Universidade Federal de Minas Gerais. He is currently a post-doctoral fellow at the Department of Computer Science at UFMG (Brazil). He has experience in the development of Web systems, Data Science and data visualization, Bioinformatics and machine learning. Has knowledge in the following languages: PHP, JavaScript, Python, R, Perl, HTML, CSS and SQL.

Orcid iD | Publons | ResearchGate


Ph.D. Bioinformatics 2019
Universidade Federal de Minas Gerais, UFMG, Brazil

M.Sc. Bioinformatics 2015
Universidade Federal de Minas Gerais, UFMG, Brazil

B.A. in Information Systems 2012
Faculdade Anhanguera de Belo Horizonte, Brazil


Postdoctoral Fellow  2019-*
Department of Computer Science, UFMG

  • Publishing papers focusing on the suggestion of mutations for biofuel enzymes
  • Supervising the undergraduate and graduate research
  • Writing research projects
  • Conducting lectures about programming for bioinformatics
  • Infrastructure management of high-performance computer servers, software development, and databases management

Research Analyst 2015-2019
Department of Computer Science, UFMG

  • Completed thesis research, supervised by a faculty mentor
  • Involved in research projects related to the rational design of enzymes used in biofuel production through data science approaches
  • Biological data collection and development of bioinformatics tools

Research Assistant 2013-2015
Institute of Biological Sciences, UFMG

  • Developed computational approaches for assembly and annotation of bacterial genomes
  • Constructed web tools for analyzing bacterial regulatory networks


  • Programming
  • Data analysis
  • Web designer
  • Database management
  • Hardware
  • Portuguese (fluent)
  • English (intermediate)
  • Spanish (intermediate)
  • French (basic)

Periodic Reviewer

Bioinformatics (ISSN 1460-2059) 2019-* | Publons


MARIANO, DIEGO; et al. Glutantβase: a database for improving the rational design of glucose-tolerant β-glucosidases. BMC Molecular and Cell Biology, v. 21, p. 50, 2020.

BARROSO, JOSÉ RENATO M. S.; MARIANO, DIEGO. Proteus: An algorithm for proposing stabilizing mutation pairs based on interactions observed in known protein 3D structures. BMC BIOINFORMATICS, v. 21, p. 275, 2020.

DE LIMA, LHF; FERNANDEZ-QUINTÉRO, M; ROCHA, REO; MARIANO, DCB; DE MELO-MINARDI, RC; LIEDL, KR. Conformational flexibility correlates with glucose tolerance for point mutations in β-glucosidases – A computational study. Journal of Biomolecular Structure and Dynamics, v. 1, p. 1-20, 2020.

MARIANO, DIEGO; et al. A Computational Method to Propose Mutations in Enzymes Based on Structural Signature Variation (SSV). INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v. 20, p. 333, 2019.

MARIANO, DIEGO; et al. Introducing Programming Skills for Life Science Students. BIOCHEMISTRY AND MOLECULAR BIOLOGY EDUCATION, v. 1, p. 21230, 2019.

COSTA, LSC; MARIANO, DCB; et al. Molecular Dynamics Gives New Insights into the Glucose Tolerance and Inhibition Mechanisms on β-Glucosidases. MOLECULES, v. 24, p. 3215, 2019.

GOMIDE, ACP; IBRAIM, IC; ALVES, JTC; DE SÁ, PG; DE OLIVEIRA SILVA, YR; SANTANA, MP; SILVA, WM; FOLADOR, EL; MARIANO, DCB; et al. Transcriptome analysis of Corynebacterium pseudotuberculosis biovar Equi in two conditions of the environmental stress. GENE, v. 8, p. 1, 2018.

SILVA, MARCOS F.M. ; MARTINS, PEDRO M. ; MARIANO, DIEGO C.B.; et al. Proteingo: motivation, user experience, and learning of molecular interactions in biological complexes. ENTERTAINMENT COMPUTING, v. 1, p. 001, 2018.

HURTADO, RAQUEL ENMA; ABURJAILE, FLAVIA; MARIANO, DIEGO; et al. Draft Genome Sequence of a Virulent Strain of Pasteurella Multocida Isolated From Alpaca. JOURNAL OF GENOMICS, v. 5, p. 68-70, 2017.

MARIANO, D.C.B.; et al. Characterization of glucose-tolerant β-glucosidases used in biofuel production under the bioinformatics perspective: a systematic review. GENETICS AND MOLECULAR RESEARCH, v. 16, p. 1-19, 2017.

ALMEIDA, SINTIA; TIWARI, SANDEEP; MARIANO, DIEGO; et al. The genome anatomy of Corynebacterium pseudotuberculosis VD57 a highly virulent strain causing Caseous lymphadenitis. Standards in Genomic Sciences, v. 11, p. 29, 2016.

MARIANO, DIEGO; et al. Whole-genome optical mapping reveals a mis-assembly between two rRNA operons of Corynebacterium pseudotuberculosis strain 1002. BMC Genomics, v. 17, p. 315, 2016.

DE AGUIAR, EDGAR LACERDA ; MARIANO, D. C. B. ; et al. Complete genome sequence of Streptococcus agalactiae strain GBS85147 serotype of type Ia isolated from human oropharynx. Standards in Genomic Sciences, v. 11, p. 1, 2016.

MARIANO, DIEGO C. B.; et al. SIMBA: a web tool for managing bacterial genome assembly generated by Ion PGM sequencing technology. BMC Bioinformatics, v. 17, p. 65-72, 2016.

ABREU, VINICIUS A. C.; ALMEIDA, SINTIA; TIWARI, SANDEEP; HASSAN, SYED SHAH; MARIANO, DIEGO; et al. CMRegNet-An interspecies reference database for corynebacterial and mycobacterial regulatory networks. BMC Genomics, v. 16, p. 452, 2015.

MARIANO, DIEGO CB; et al. MapRepeat: an approach for effective assembly of repetitive regions in prokaryotic genomes. BIOINFORMATION (ONLINE) (CHENNAI), v. 11, p. 276-279, 2015.


OLIVEIRA JUNIOR, A. F. ; BENEVIDES, LEANDRO DE JESUS ; MARIANO, D. C. B. ; AGUIAR, E. L. ; SOUSA, T. J. ; SILVA, A. ; AZEVEDO, V. A. C. . Bioinformatics. In: Zahoorullah S MD. (Org.). A Textbook of Biotechnology. 1ed.: SMGroup, 2015, v. , p. 15-32.